There are 8 independent PWM generators called slices, which each have two channels making it 16 PWM channels in total which can be clocked from 8Hz to 62.5Mhz at a machine.freq() of 125Mhz. The two channels of a slice run at the same frequency, but can have a different duty rate. The two channels are usually assigned to adjacent GPIO pin pairs with even/odd numbers. So GPIO0 and GPIO1 are at slice 0, GPIO2 and GPIO3 are at slice 1, and so on. A certain channel can be assigned to different GPIO pins (see Pinout). For instance slice 0, channel A can be assigned to both GPIO0 and GPIO16.

Use the machine.PWM class:

from machine import Pin, PWM

# create PWM object from a pin and set the frequency of slice 0
# and duty cycle for channel A
pwm0 = PWM(Pin(0), freq=2000, duty_u16=32768)
pwm0.freq()             # get the current frequency of slice 0
pwm0.freq(1000)         # set/change the frequency of slice 0
pwm0.duty_u16()         # get the current duty cycle of channel A, range 0-65535
pwm0.duty_u16(200)      # set the duty cycle of channel A, range 0-65535
pwm0.duty_u16(0)        # stop the output at channel A
print(pwm0)             # show the properties of the PWM object.
pwm0.deinit()           # turn off PWM of slice 0, stopping channels A and B